KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX12
All Species:
17.27
Human Site:
S608
Identified Species:
29.23
UniProt:
Q92771
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92771
NP_004391
950
106006
S608
V
I
L
S
R
Q
G
S
L
S
Q
S
T
L
K
Chimpanzee
Pan troglodytes
XP_520821
925
103112
S608
V
I
L
S
R
Q
G
S
L
S
Q
S
T
L
K
Rhesus Macaque
Macaca mulatta
XP_001114477
931
104280
S589
V
I
L
S
R
Q
G
S
L
S
Q
S
T
L
K
Dog
Lupus familis
XP_543872
907
102087
S590
V
I
L
S
R
Q
G
S
L
S
Q
S
S
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q6AXC6
880
98710
G560
R
V
I
V
N
R
Q
G
S
V
G
Q
S
S
L
Rat
Rattus norvegicus
XP_001070646
845
94905
N538
S
L
K
F
L
L
L
N
P
A
V
H
F
A
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517598
930
104705
S620
I
I
L
N
H
Q
S
S
L
S
L
S
S
L
K
Chicken
Gallus gallus
XP_416375
940
105739
I620
A
N
E
D
G
R
V
I
L
N
R
Q
G
T
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007320
890
100643
I567
N
K
D
G
R
I
V
I
Q
R
Q
A
C
V
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569898
861
96577
G563
I
L
V
D
P
V
G
G
T
L
K
Y
I
L
L
Honey Bee
Apis mellifera
XP_001121183
769
88327
Q495
P
M
N
E
F
I
E
Q
L
F
I
A
A
G
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792082
780
88384
V506
D
F
K
H
Q
L
F
V
C
T
G
V
Q
P
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P22516
861
98787
V579
I
L
N
Q
A
K
C
V
V
L
A
G
G
T
M
Red Bread Mold
Neurospora crassa
A7UXD4
1073
119198
H694
Y
M
L
L
S
P
T
H
A
F
S
S
I
A
E
Conservation
Percent
Protein Identity:
100
94.4
92.4
78.3
N.A.
72.3
67.7
N.A.
71.3
67.7
N.A.
57.2
N.A.
37.5
36.3
N.A.
45.4
Protein Similarity:
100
95.8
94.4
85.2
N.A.
80
76.2
N.A.
81.7
80.2
N.A.
73.4
N.A.
53.6
53.7
N.A.
61
P-Site Identity:
100
100
100
93.3
N.A.
0
0
N.A.
60
6.6
N.A.
13.3
N.A.
13.3
6.6
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
26.6
26.6
N.A.
80
26.6
N.A.
26.6
N.A.
40
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.2
25.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.5
43.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
0
0
0
8
8
8
15
8
15
15
% A
% Cys:
0
0
0
0
0
0
8
0
8
0
0
0
8
0
0
% C
% Asp:
8
0
8
15
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
8
0
0
8
0
0
0
0
0
0
0
15
% E
% Phe:
0
8
0
8
8
0
8
0
0
15
0
0
8
0
0
% F
% Gly:
0
0
0
8
8
0
36
15
0
0
15
8
15
8
0
% G
% His:
0
0
0
8
8
0
0
8
0
0
0
8
0
0
0
% H
% Ile:
22
36
8
0
0
15
0
15
0
0
8
0
15
0
8
% I
% Lys:
0
8
15
0
0
8
0
0
0
0
8
0
0
0
36
% K
% Leu:
0
22
43
8
8
15
8
0
50
15
8
0
0
43
15
% L
% Met:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
8
8
15
8
8
0
0
8
0
8
0
0
0
0
0
% N
% Pro:
8
0
0
0
8
8
0
0
8
0
0
0
0
8
0
% P
% Gln:
0
0
0
8
8
36
8
8
8
0
36
15
8
0
8
% Q
% Arg:
8
0
0
0
36
15
0
0
0
8
8
0
0
0
0
% R
% Ser:
8
0
0
29
8
0
8
36
8
36
8
43
22
8
0
% S
% Thr:
0
0
0
0
0
0
8
0
8
8
0
0
22
15
0
% T
% Val:
29
8
8
8
0
8
15
15
8
8
8
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _